Over the next few years the mechanism underlying RNA interference was established from work on diverse organisms, especially the worm and the fruit fly. RNA interference was considered to be an evolutionarily ancient mechanism for protecting organisms from viruses. Many viruses have RNA, rather than DNA, as their genetic material and go through at least one stage in their life cycle in which they make double stranded RNA. All multicellular organisms possess a conserved protein machinery that recognises double stranded RNA.
Халявное ревью 2004 года, с красивыми схемами. http://bmj.bmjjournals.com/cgi/content/full/328/7450/1245
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timeasmymeasure
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Date: 2004-09-30 03:55 am (UTC)Over the next few years the mechanism underlying RNA interference was established from work on diverse organisms, especially the worm and the fruit fly. RNA interference was considered to be an evolutionarily ancient mechanism for protecting organisms from viruses. Many viruses have RNA, rather than DNA, as their genetic material and go through at least one stage in their life cycle in which they make double stranded RNA. All multicellular organisms possess a conserved protein machinery that recognises double stranded RNA.
Халявное ревью 2004 года, с красивыми схемами. http://bmj.bmjjournals.com/cgi/content/full/328/7450/1245